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Overview
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CD14 is a 55kDa glycosyl-phosphatidylinositol-linked membrane protein, involved in endotoxin bindingand recognition of apoptotic cells. CD14 is expressed on monocytes, macrophages, follicular dendriticcells, and granulocytes. Anti-CD14 can detect these cells, including monocyte-derived cells which arefrequently increased in diffuse large B-cell lymphoma (DLBCL), as well as in neoplastic cells in acutemyeloid leukemia with monocytic differentiation and chronic myelomonocytic leukemia.
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