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Overview
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CD15 is a carbohydrate antigen with the common trisaccharide structure 3-fucosyl-N-acetyl-lactosamine, also known as Lewis x (Lex) or stage-specific embryonic antigen 1 (SSEA-1). CD15 isexpressed in myeloid cells and mediates neutrophil adhesion to dendritic cells. CD15 is alsoexpressed in Reed-Sternberg cells and is thus a useful marker for identifying Hodgkin's lymphoma.
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Overview