Anti-CD11a antibody

Catalog Number:

IGA1027853STJ

Mfr. No.:

STJ16100022

Price:

$465

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Overview
- Reacts with CD11a, a transmembrane molecule with 1145 amino acid residues and a MW of180 kDa. CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages. Levels onmemory T-cells tend to increase. CD11a plays a key role in mediating leukocyte adhesion toendothelium during inflammatory response through binding to ICAM 1 (CD54). Other ligands areICAM-2 and ICAM-3. It is also involved in many other T-cell functions and immune phenomena. Whenpaired with CD18, it forms the integrin alphaL beta2 adhesion.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2b kappa
  
  Reactivity
  
  human
  
  Clone
  
  87-6F9
  
  Immunogen
  
  stimulated human leucocytes
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  100 µg of purified antibody in PBS with 0, 02% sodium Azide.
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Integrin Alpha-L; Cd11 Antigen-Like Family Member A; Leukocyte Adhesion Glycoprotein Lfa-1 Alpha Chain; Lfa-1a; Leukocyte Function-Associated Molecule 1 Alpha Chain; Cd Antigen Cd11a (Gene ID:3683; UniProt:P20701)
  
  * For research use only