Anti-CD11a antibody

Anti-CD11a antibody

Catalog Number:
IGA1027853STJ
Mfr. No.:
STJ16100022
Price:
$465
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      • Overview
        • Reacts with CD11a, a transmembrane molecule with 1145 amino acid residues and a MW of180 kDa. CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages. Levels onmemory T-cells tend to increase. CD11a plays a key role in mediating leukocyte adhesion toendothelium during inflammatory response through binding to ICAM 1 (CD54). Other ligands areICAM-2 and ICAM-3. It is also involved in many other T-cell functions and immune phenomena. Whenpaired with CD18, it forms the integrin alphaL beta2 adhesion.

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG2b kappa
          Reactivity
          human
          Clone
          87-6F9
          Immunogen
          stimulated human leucocytes
          Conjugate
          Unconjugated
          Formulation
          100 µg of purified antibody in PBS with 0, 02% sodium Azide.
          Storage
          Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Integrin Alpha-L; Cd11 Antigen-Like Family Member A; Leukocyte Adhesion Glycoprotein Lfa-1 Alpha Chain; Lfa-1a; Leukocyte Function-Associated Molecule 1 Alpha Chain; Cd Antigen Cd11a (Gene ID:3683; UniProt:P20701)

          * For research use only

      • Applications
        • Application
          IHC (frozen); Flow Cytometry; IF
        • Application Dilutions
          FC 0.5-1.0 μg/million cells in 0.1 ml
          IHC (Frozen)
          IF 1.0-2.0 μg/ml
          Functional Assays 0. 02-2.0 μg/ml without azide

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