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Overview
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Reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class Imolecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class Iantigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed onmany types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.Immunogen: Purified human beta2-microglobulin
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Overview