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Overview
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Anagyrine is a teratogenic quinolizidine alkaloid found in Lupinus sp. which undergoes metabolism to a piperidine that causes crooked calf syndrome. Anagyrine, but not lupanine or sparteine, directly desensitize nicotinic acetylcholine receptors (nAChR) in a cell culture model. Anagyrine is reported to have antiarrhythmic, tachycardic, diuretic and purgative properties. Extracts containing anagyrine have antifungal activity.
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