Alvimopan

Alvimopan

Catalog Number:
MAR1341481TOK
Mfr. No.:
TOK-A172
Price:
$229
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      • Overview
        • Alvimopan is a gastroprokinetic peripherally restricted mu-opioid receptor antagonist (MOR). It has a favorable kinetic activity (0.2 ng/ml) and dissociates more slowly than most other ligands.

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          Background

          Alvimopan competitively binds to the mu-opioid receptor in the gastrointestinal tract. It has a low systemic absorption and a high affinity for mu-opioid receptors. This compound assists gastrointestinal motility dysfunction.

      • Properties
        • Categories
          BioActive Small Molecules
          CAS Number
          156053-89-3
          Molecular Formula
          C25H32N2O4
          Molecular Weight
          424.53
          Appearance
          White to off-white powder
          Solubility
          Slightly soluble in DMSO. Very slightly soluble in water.
          Other Properties
          Source: Synthetic
          Purity Level: 98.0%-102.0% (anhydrous basis)02.0% (anhydrous basis)
          Storage
          2-8°C (protect from light)

          * For research use only

      • Applications
        • Application Description
          Eukaryotic Cell Culture Applications: In vitro studies with Alvimopan using CHO cell membranes revealed that it inhibited GTP binding with an IC50 of 1.7 nM.

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