Amphotericin B - Amerigo Scientific

- Overview
  - Amphotericin B is a macrocycle antibiotic first isolated from Streptomyces nodosus. Its antifungal activity is exerted by interacting with the fungal membrane, mainly ergosterol, and inducing pore formation. The increase in membrane permeability causes loss of ions and cell death. The C-2’ hydroxyl residue of the mycosamine carbohydrate moiety in the structure seems to have a major role in binding to ergosterol. It is used in cell culture to prevent growth of microbial contaminants, such as yeast and fungi. It is recommended by the WHO and CDC as an antifungal component for VTM at a concentration of 250ug/ml.
    
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- Properties
  - Categories
    
    Antibiotics
    
    CAS Number
    
    1397-89-3
    
    Molecular Formula
    
    C47H73NO17
    
    Molecular Weight
    
    924.08 g/mol
    
    MDL Number
    
    MFCD00877763
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use