Amoxicillin : Potassium Clavulanate (2:1)

Amoxicillin : Potassium Clavulanate (2:1)

Catalog Number:
PB01342636TOK
Mfr. No.:
TOK-A054
Price:
$216
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      • Overview

        • Please contact us at for specific academic pricing.

          Background

          Like all β-lactams, Amoxicillin targets PBP’s (penicillin binding proteins) involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised ultimately leading to the death of the cell.

      • Properties
        • CAS Number
          Mixture
          Appearance
          Off-white or yellow powder
          Solubility
          Freely soluble in water (300 mg/ml)
          Other Properties
          PH: 4.8-8.6
          Purity Level: Amoxicillin: ≥54.0%Clavulanic Acid: ≥26.8%
          Storage
          -20°C

          * For research use only

      • Applications
        • Application Description
          Spectrum: Amoxicillin targets a wide range of β-lactamase negative Gram-positive and Gram-negative bacteria including E. coli and a number of Streptococcus and Staphylococcus species. Because peptidoglycan is synthesized in Gram-positive and Gram-negative bacteria, Amoxicillin can be used against a wide variety of microbes. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.

          Microbiology Applications: Amoxicillin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive and Gram-negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options. Representative MIC values include:
          Neisseria gonorrhoeae 0.3 µg/mL - 32 µg/mL
          Haemophilus influenzae 0.125 µg/mL － >64 µg/mL
    MSDS

    Documents

    MSDS-EU

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