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Overview
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WIN 66306 is a cyclic peptide discovered during a search for inhibitors of Substance P binding to neurokinin (NK) receptors by Sterling Winthrop Pharmaceuticals in 1994. WIN 66306, isolated from Aspergillus sp., is active at both the NK1 and NK2 receptor subtypes and is more active against human NK1 receptors than rat NK1 receptors.
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