Name: Sulbenicillin Sodium
Price: 198.00 USD

- Overview
  - Sulbenicillin sodium is the sodium salt of sulbenicillin. Sulbenicillin is a broad-spectrum semisynthetic penicillin antibiotic.
    
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    Background
    
    Sulbenicillin differs from carbenicillin in having a sulfo group instead of a carboxy group in the a-position. The compound acts on the peptidoglycan layer.
- Properties
  - CAS Number
    
    28002-18-8
    
    Molecular Formula
    
    C16H16N2O7S2 • Na2
    
    Molecular Weight
    
    458.42
    
    Appearance
    
    White to off-white powder
    
    Solubility
    
    Water (91 mg/ml), DMSO (91 mg/ml) Ethanol: insoluble
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Effective against Gram-positive and Gram-negative bacteria including Pseudomonas aeruginosa.
    
    Eukaryotic Cell Culture Applications: An in vitro, cell culture system using the MTT for drug toxicity to the corneal endothelium was developed. The MTT assay was used to test cytotoxicity of Sulbenicillin to cultured porcine corneal endothelial cells. In its original 10-fold intracameral injection dose, the drug was considered safe and did not show any cytotoxicity. It was only toxic at a 100-fold intracameral injection dose. This in vitro method has the following advantages over in vivo methods: it is quick, convenient, and economical, and large numbers of toxic compounds can be compared side-by-side. (Wang et al, 1996).