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Overview
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Retapamulin is a semi-synthetic pleuromutilin prepared by reacting pleuromutilin tosylate with tropine-3-thiol to give a more hydrophobic analogue with a tertiary amine. This enables formulation as a stable hydrochloride salt. Retapamulin is a broad spectrum antibiotic with no cross resistance to existing antibiotic classes, and is the first pleuromutilin approved for human use.
Retapamulin is soluble in ethanol, methanol, DMF and DMSO and has moderate water solubility.Please contact us at for specific academic pricing.
Background
Retapamulin inhibits protein synthesis by binding to domain V of 23S rRNA.
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- Properties
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Overview
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