Penicillin V potassium

Penicillin V potassium

Catalog Number:
M001342278TOK
Mfr. No.:
TOK-P027
Price:
$156
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      • Overview
        • Penicillin is a member of the β-lactam antibiotics and was one of the first discovered antibiotics.
          Penicillin V potassium is sparingly soluble in aqueous solution at 1 mg/mL.

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          Background

          β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases.

      • Properties
        • CAS Number
          132-98-9
          Molecular Formula
          C16H17N2O5SK
          Molecular Weight
          388.48
          Appearance
          Yellow crystalline powder
          Solubility
          Water: Freely soluble
          Other Properties
          Source: Penicillium Spp.
          Melting Point: 197-202 °C
          Purity Level: ≥85.0%
          Storage
          2-8 °C

          * For research use only

      • Applications
        • Application Description
          Spectrum: Penicillin is targets primarily gram positive bacteria including Staphylococcus and Streptococcus species.

          Microbiology Applications: Penicillin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram positive microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients. Representative MIC values include:Streptococcus pneumoniae 0.004 µg/mL – 0.5 µg/mLStreptococcus agalactiae 0.03 µg/mL – 0.06 µg/mL

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