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Overview
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PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM). Treatment of cells with PYR-41 inhibits overall protein ubiquitination, prevents ubiquitin-mediated proteasomal degradation, and inhibits pathways mediated by the ubiquitin-proteasome. It has also been found that PYR-41 treatment increases protein sumoylation in cells.
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- Properties
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Overview
PYR-41
PYR-41
Catalog Number:
I002097686UBP
Mfr. No.:
F5101
Price:
$520
Size:
25 mg
Quantity:
Add to Cart: