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PYR-41

PYR-41

Catalog Number:
I002097687UBP
Mfr. No.:
F5100
Price:
$250
  • Size:
    5 mg
    Quantity:
    Add to Cart:
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      • Overview

        • PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM). Treatment of cells with PYR-41 inhibits overall protein ubiquitination, prevents ubiquitin-mediated proteasomal degradation, and inhibits pathways mediated by the ubiquitin-proteasome. It has also been found that PYR-41 treatment increases protein sumoylation in cells.

          Please contact us at for specific academic pricing.

      • Properties
        • Protein Name
          4[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester
          Source
          Synthetic
          Formulation
          Powder
          Storage
          Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light.
          Concentration
          N/A
          Molecular Weight
          371.3 g/mol

          * Research Use Only

    Datasheet

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