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PYR-41

PYR-41

Catalog Number:

I002097687UBP

Mfr. No.:

F5100

Price:

$250

Size:

5 mg

Quantity:

Add to Cart:

- Overview
  - PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM). Treatment of cells with PYR-41 inhibits overall protein ubiquitination, prevents ubiquitin-mediated proteasomal degradation, and inhibits pathways mediated by the ubiquitin-proteasome. It has also been found that PYR-41 treatment increases protein sumoylation in cells.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    4[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester
    
    Source
    
    Synthetic
    
    Formulation
    
    Powder
    
    Storage
    
    Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light.
    
    Concentration
    
    N/A
    
    Molecular Weight
    
    371.3 g/mol
    
    * Research Use Only

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