Paromomycin sulfate

- Overview
  - Paromomycin sulfate is a freely soluble (50 mg/mL) aminoglycoside antibacterial and antiparasitic drug.
    
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    Background
    
    Like many aminoglycosides, paromomycin targets the 16S rRNA of the 30S ribosomal subunit and prevents translocation and misreading of mRNA by stabilizing aminoacyl-tRNA in the acceptor (“A”) site.
- Properties
  - CAS Number
    
    1263-89-4
    
    Molecular Formula
    
    C23H45N5O14 · H2SO4
    
    Molecular Weight
    
    713.71 g/mol
    
    Appearance
    
    White or almost white powder
    
    Solubility
    
    Water: <50 mg/mL
    
    Other Properties
    
    PH: 5.0-7.5
    Boiling Point: 939.8 °C
    Melting Point: >200 °C
    
    Storage
    
    2-8 °C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Paromomycin is a broad spectrum antibiotic targeting a wide range of gram positive and gram negative bacteria including Escherichia coli and Staphylococcus species.