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Overview
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MycoRid™ is a highly stable, solubilized aqueous formulation (1000x) of a polyene antifungal compound. It is a substitute for Amphotericin B (Fungizone). It has a lower level of cytotoxicity in cell culture due to the use of polysaccharide as a solubilizing agent, rather than sodium deoxycholate in Fungizone that has shown evidence of cytotoxicity in cell culture. MycoRid can be stored up to 3 months at 4°C, unlike Amphotericin B solution that is stable for one month at 4°C.
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Background
The active component of MycoRid™ has a similar mode of action to Amphotericin B (Fungizone). Polyene antimicrobials associate with membrane sterols in mammalian and fungal cell membranes and forms pores leading to essential ion leakage and ultimately, cell death.
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- Properties
- Applications
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Overview