MT1 Melatonin Receptor - Class A GPCR

MT1 Melatonin Receptor - Class A GPCR

Catalog Number:
P001026869CAL
Mfr. No.:
PP2
Price:
$1,194
  • Size:
    10µg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • CALIXAR’s MT1 (Melatonin receptor 1) helps you identify, develop, and test new molecules and therapeutic antibodies for CNS neuroprotection treatments for insomnia, circadian sleep disorders, depression, cardiovascular regulation, cancer, and neurodegenerative diseases.

          Please contact us at for specific academic pricing.

          Background

          Our Melatonin receptor 1 (MT1) is a class A GPCR that modulates neuronal firing, arterial vasoconstriction, cell proliferation in cancer cells, and reproductive and metabolic functions.

          More Details

          CALIXAR
          Purified Membrane Proteins
      • Properties
        • Source
          Human
          Purification
          Metal Affinity Chromatography in presence of Sarkosyl/CHS (Pruity: >90%)
          Formulation
          25mM Na2HPO4 pH 8.0, 150mM NaCl, 0.86%/0.18% Sarkosyl/CHS as sample buffer
          Storage
          Store at -80°C​
          Concentration
          Up to 5mg/ml
          Molecular Weight
          44,8kDa
          Class
          Membrane Proteins
          Expression system
          Sf9 insect cells (baculovirus)​
          Sequence
          Full-length, wildtype sequence, with a N-terminus Strep tag II, 8xHis-tag, and TEV protease cleavage site.
          Activity
          Confirmed by radiobinding assay and activation of Gi

          More Information

          UniProt
          P48039

          * For Research Use Only

      • Applications
        • Application Description
          CALIXAR’s MT1 (Melatonin receptor 1) helps you identify, develop, and test new molecules and therapeutic antibodies for CNS neuroprotection treatments for insomnia, circadian sleep disorders, depression, cardiovascular regulation, cancer, and neurodegenerative diseases.
      • Reference
    Datasheet

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