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Overview
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CALIXAR’s KCC2 (Neuron-specific K-Cl Cotransporter) aids in the exploration, advancement, and validation of new molecules as well as therapeutic antibodies. They are ideal candidates for neurological disorders including pain and epilepsy.
Please contact us at for specific academic pricing.
Background
This plasma membrane neuron-specific chloride potassium symporter is responsible for establishing the chloride ion gradient in neurons through the maintenance of low intracellular chloride concentrations. It is a critical mediator of synaptic inhibition, cellular protection against excitotoxicity and may also act as a modulator of neuroplasticity.
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