Milbemycin A4 oxime

- Overview
  - Milbemycin A4 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of milbemycin A4. Milbemycin A4 oxime is the major component (~70%) in the commercial product, milbemycin oxime, marketed for endo- and exo-parasite infections.
    
    Milbemycin A4 oxime is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Like the other milbemycin/avermectins, milbemycin A4 oxime acts by opening glutamate sensitive chloride channels in neurons of invertebrates, leading to paralysis by hyperpolarisation of these cells and signal transfer blocking.
- Properties
  - CAS Number
    
    93074-04-5
    
    Molecular Formula
    
    C32H45NO7
    
    Molecular Weight
    
    555.7
    
    Appearance
    
    White solid
    
    Storage
    
    -20°C
    
    * For research use only