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Overview
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Milbemycin A3 belongs to the family of Milbemycins, 16-membered macrocyclic lactone antibiotics with a 6,6-membered spiroketal ring system. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Milbemycin A3 is a major member of a group of analogs containing a 25-methyl substituent. Milbemycin A3 is a metabolite derived from fermentation of the soil bacterium Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycins are analogs of the avermectins. Other Milbemycins include Milbemycin B through H.
Milbemycin A3 is soluble in ethanol, methanol, DMF and DMSO but has poor water solubility.Please contact us at for specific academic pricing.
Background
Like the closely related avermectins, Milbemycins are thought to act by opening glutamate sensitive and GABA-sensitive chloride channels.
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- Properties
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Overview