Name: Mca-RPKPVE-Nval-WR-K(Dnp)-NH2
Price: 298.00 USD

- Overview
  - Fret substrate for MMP-3 and MMP-10.
    Mca-RPKPVE-Nval-WRK(Dnp)-NH2, also known as Mca-RPKPVE-Nval-WRK(Dnp)-NH2 Fluorogenic MMP Substrate, is an excellent substrate for MMP-3 (stromelysin 1) and MMP-10 (stromelysin 2), but not a substrate MMP-1 or MMP-2. Mca-RPKPVE-Nval-WRK(Dnp)-NH2 substrate contains a highly fluorescent 7-methoxycoumarin (Mca) group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl (Dnp) group. The cleavage site is the peptide bond between Glu and Nval (norvaline). Mca-RPKPVE-Nval-WRK(Dnp)-NH2 is also an excellent substrate for trypsin, HGF activator and factor Xa.
    
    Please contact us for availability.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Fluorescent Labelled Peptides
    
    Alternative Name
    
    Mca-RPKPVE-Nval-WRK(Dnp)-NH2 fluorogenic MMP substrate
    
    Molecular Formula
    
    C78H110N22O20
    
    Molecular Weight
    
    1675.9
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in DMSO
    
    Other Properties
    
    Sequence: Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(Dnp)-NH2,Mca-RPKPVEXWRK(Dnp)-NH2
    Modification: 7-methoxycoumarin (Mca) at the N terminal, X is norvaline, Lysine 10 is substuted with a 2,4-dinitrophenyl (Dnp) group, and the C terminal is amidated
    
    Storage
    
    Store desiccated, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Mca-RPKPVE-Nval-WR-K(Dnp)-NH2

Mca-RPKPVE-Nval-WR-K(Dnp)-NH2

We Also Recommend

Mca-RPPGFSAFK(Dnp)-OH

Mca-SEVNLDAEFR-K(Dnp)-RR-NH2

Mca-YVADAP-K(Dnp)-OH