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Mca-YVADAP-K(Dnp)-OH

Mca-YVADAP-K(Dnp)-OH

Catalog Number:
P004516733LIF
Mfr. No.:
PEPTIDE-PS-030
Price:
$298
  • Size:
    1mg
    Quantity:
    Add to Cart:
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      • Overview

        • FRET substrate for caspase-1.
          Mca-YVADAP-K(Dnp)-OH, or Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH, is a highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp)-OH at the P1 Asp residue results in a continuous fluorescent assay which can be monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Mca-YVADAP-K(Dnp)-OH is a specific substrate for renal ACE 2.

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          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Fluorescent Labelled Peptides
          Alternative Name
          Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH
          Molecular Formula
          C53H64N10O19
          Molecular Weight
          1145.1
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in DMSO
          Other Properties
          Sequence: Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH,Mca-YVADAPK(Dnp)
          Modification: 7-methoxycoumarin (Mca) at N terminal, 2,4-dintrophenyl on lysine 7
          Storage
          Store desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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