Name: Mca-PLGL-Dap(Dnp)-AR-NH2
Price: 298.00 USD

- Overview
  - FRET substrate for matrix metalloproteinases.
    Mca-PLGL-Dap(Dnp)-AR-NH2 is a sensitive synthetic peptide FRET substrate for the determination of matrix metalloproteinase (MMP) activity. Protease cleavage at the -Gly-Leu- bond releases the highly fluorescent 7-methoxycoumarin (Mca) group from the influence of the 2,4-dinitrophenyl (Dnp) internal quencher, resulting in a 190 fold increase in fluorescence intensity. Mca-PLGL-Dap(Dnp)-AR-NH2 is suitable for use in continuous assays at enzyme concentrations comparable to those used with macromolecular substrates and also for the assessment of total matrix metalloproteinase in crude preparations.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Fluorescent Labelled Peptides
    
    Molecular Formula
    
    C49H68N14O15
    
    Molecular Weight
    
    1093.2
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in DMSO
    
    Other Properties
    
    Sequence: Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2,Mca-PLGLX(Dnp)AR-NH2
    Modification: Mca (7-methoxycoumarin) on N terminal, C terminal is amidated, X is diaminopropionic acid substituted with 2,4-dinitrophenyl (Dnp)
    
    Storage
    
    Store desiccated, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Mca-PLGL-Dap(Dnp)-AR-NH2

Mca-PLGL-Dap(Dnp)-AR-NH2

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