Name: MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2
Price: 381.00 USD

- Overview
  - FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro).
    MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 is a FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro). The MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 substrate sequence is derived from residues P4 ?P5′ of the SARS-CoV Mpro N-terminal autoprocessing site which has the sequence AVLQSGFRK. Enzmatic cleavage between Q4 and S5 of MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 releases the highly fluorescent 7-methoxycoumarin (Mca) group from the influence of the 2,4-dinitrophenyl (Dnp) internal quencher, resulting in a large increase in fluorescence intensity.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Fluorescent Labelled Peptides
    
    Alternative Name
    
    SARS Main Protease FRET Substrate
    
    Molecular Formula
    
    C69H99N19O20
    
    Molecular Weight
    
    1514.7
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble as a stock solution in DMSO
    
    Other Properties
    
    Sequence: Mca-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys(Dnp)-Lys-NH2,Mca-AVLQSGFRK(Dnp)K-NH2
    Modification: N terminal 7-methoxycoumarin (Mca), C terminal amide, lysine 9 has 2,4-dinitrophenyl (Dnp) attached
    
    Storage
    
    Store desiccated, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2

MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2

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