LDN-57444

LDN-57444

Catalog Number:
I002097712UBP
Mfr. No.:
F2104-5
Price:
$260
  • Size:
    5 mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • LDN-57444 is a potent small chemical inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1, IC50 = 0.88 μM). UCHL1 functions to generate free ubiquitin from ubiquitin precursors. Loss of UCH-L1 activity causes apoptosis due to an impaired ubiquitin-proteasome pathway. LDN-57444-induced reduction of free ubiquitin could increase spine size while decreasing spine density in hippocampal neurons.

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      • Properties
        • Protein Name
          LDN57444, UCHL1 inhibitor
          Source
          Synthetic
          Formulation
          C17H11Cl3N2O3
          Storage
          Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light
          Molecular Weight
          397.6 g/mol

          * Research Use Only

    Datasheet
    MSDS

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