Human CLDN9 full length protein-synthetic nanodisc

Human CLDN9 full length protein-synthetic nanodisc

Catalog Number:
P001561742DIM
Mfr. No.:
FLP100081
Price:
$1,013
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      • Overview

        • Target: CLDN9
          Tag: C-Flag Tag
          Synonyms: DFNB116
          Protein Families: Transmembrane
          Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction

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          Background

          This protein is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness.

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length CLDN9 protein has a MW of 22.8 kDa
          Expression system
          HEK293

          More Information

          UniProt
          O95484

          * For research use only.

    MSDS

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