Human CLDN5 full length protein-synthetic nanodisc

Human CLDN5 full length protein-synthetic nanodisc

Catalog Number:
P001561743DIM
Mfr. No.:
FLP100079
Price:
$1,013
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      • Overview
        • Target: CLDN5
          Tag: C-Flag Tag
          Synonyms: AWAL; BEC1; CPETRL1; TMDVCF; TMVCF
          Protein Families: Transmembrane
          Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction

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          Background

          This protein is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length CLDN5 protein has a MW of 23.1 kDa
          Expression system
          HEK293

          More Information

          UniProt
          O00501

          * For research use only.

    Documents

    Datasheet