Human CD151 full length protein-synthetic nanodisc

Human CD151 full length protein-synthetic nanodisc

Catalog Number:
P001561745DIM
Mfr. No.:
FLP100071
Price:
$1,013
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      • Overview
        • Target: CD151
          Tag: C-Flag Tag
          Synonyms: GP27; MER2; PETA-3; RAPH; SFA1; TSPAN24
          Protein Families: Druggable Genome, Transmembrane

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          Background

          The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length CD151 protein has a MW of 28.3 kDa
          Expression system
          HEK293

          More Information

          UniProt
          P48509

          * For research use only.

    Documents

    Datasheet