Gramicidin

- Overview
  - Gramicidin is a combination of six different antimicrobial polypeptides. Gramicidin is insoluble in aqueous solution.
    
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    Background
    
    Gramicidin targets and inserts into the gram positive membrane where it disrupts normal permeability leading to cell death. Gramicidin is typically used as a topical antimicrobial agent because it also causes hemolysis of red blood cells
- Properties
  - CAS Number
    
    1405-97-6
    
    Molecular Formula
    
    Gramicidin A1: C99H140N20O17
    
    Molecular Weight
    
    Gramicidin A1: 1882.29
    
    Appearance
    
    White or almost White Crystalline Powder
    
    Solubility
    
    Acetic acid: Soluble
    Lower alcohols: Soluble
    Water: Almost insoluble
    
    Other Properties
    
    Source: Bacillus Brevis
    
    Storage
    
    2-8°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Gramicidin targets primarily the cell membrane of Gram positive bacteria and shows little effect against Gram negative bacteria.