Geninthiocin

- Overview
  - Geninthiocin is a thiopeptide antibiotic isolated from a Streptomyces sp. Geninthiocin displays a 10-fold selectivity for bacteria over mammalian cells lines, whereas the related dedialanyl geninthiocin shows the reverse selectivity. Geninthiocin is closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.
    
    Geninthiocin is soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Geninthiocin is a potent activator of the tipA gene, a bacterial transcription regulator involved in multidrug resistance.
- Properties
  - CAS Number
    
    158792-27-9
    
    Molecular Formula
    
    C50H49N15O15S
    
    Molecular Weight
    
    1132.1
    
    Appearance
    
    White Amorphous Powder
    
    Storage
    
    -20°C
    
    * For research use only