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Overview
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Gageostatin A is an antimicrobial peptide (AMP) isolated from a marine strain of Bacillus subtilis. Gageostatin A is a linear lipopeptide composed of 7 peptides, and has shown initial bioactivity against pathogenic fungi, Gram-positive and Gram-negative bacteria, and cancer cell lines. Lipopeptides are nonribosomal oligopeptides made by large multienzyme complex and have a cyclic structure including β-amino or β-hydroyxl fatty acid that is integrated into the peptide moiety.
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Background
Lipopeptides may disrupt the cell membrane, thus affecting the transmembrane electric potential.
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- Properties
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Overview
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