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Overview
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Glucosylceramide (Glc-Cer) is the common precursor in the biosynthesis of most glycosphingolipids, with exception of some Gal-Cer derivatives, such as, GM4. Glucosylceramide consists of a glucosyl moiety which is β-O-glycosydically linked to ceramide, which itself, consists of the long-chain aminoalcohol sphingosine and a fatty acid. Glucosylceramide (also called glucocerebroside) is synthesised enzymatically, by the glucosylceramide synthase-catalysed with the addition of a glucose residue to ceramide. Glucosylceramide is involved in the regulation of various cellular events and also serves as a main constituent in liposome formulations.
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- Properties
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Overview