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Kaempferol

Kaempferol

Catalog Number:

FC01367263APE

Mfr. No.:

APE-N1719

Price:

$196

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- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Naturally occurring flavonoid found in Gingko biloba and red wines that activates the mitochondrial Ca2+ uniporter (EC50 = 7 μM). Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro.
- Properties
  - Categories
    
    Apoptosis inducer; antioxidant; flavonoid
    
    Alternative Name
    
    Kempferol; 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
    
    CAS Number
    
    520-18-3
    
    Molecular Formula
    
    C15H10O6
    
    Molecular Weight
    
    286.24
    
    Appearance
    
    A solid
    
    Purity
    
    99.45%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; ≥12.25 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
    
    * For Research Use Only
- Reference
  - 1. Wenling Tu, Yinjie Hong, et al. "Effect of kaempferol on hedgehog signaling pathway in rats with --chronic atrophic gastritis – Based on network pharmacological screening and experimental verification." Biomed Pharmacother. 2022 Jan;145:112451. PMID:34839256

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

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