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Kaempferol

Kaempferol

Catalog Number:
FC01367263APE
Mfr. No.:
APE-N1719
Price:
$196
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      • Overview

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          Background

          Naturally occurring flavonoid found in Gingko biloba and red wines that activates the mitochondrial Ca2+ uniporter (EC50 = 7 μM). Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro.

      • Properties
        • Categories
          Apoptosis inducer; antioxidant; flavonoid
          Alternative Name
          Kempferol; 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
          CAS Number
          520-18-3
          Molecular Formula
          C15H10O6
          Molecular Weight
          286.24
          Appearance
          A solid
          Purity
          99.45%
          Solubility
          insoluble in H2O; insoluble in EtOH; ≥12.25 mg/mL in DMSO
          Storage
          Store at -20°C
          SMILES
          C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

          * For Research Use Only

      • Reference

        • 1. Wenling Tu, Yinjie Hong, et al. "Effect of kaempferol on hedgehog signaling pathway in rats with --chronic atrophic gastritis – Based on network pharmacological screening and experimental verification." Biomed Pharmacother. 2022 Jan;145:112451. PMID:34839256

    Documents

    COA (Certificate Of Analysis)

    HPLC (Retest)

    MSDS (Material Safety Data Sheet)

    Datasheet

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