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Overview
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FR 179642 is a member of the echinocandin antifungal family patented in 1991 by Ueda and colleagues at Fujisawa, now
Astellas Pharma. FR 179642 is formed by the selective hydrolysis of FR 901379 using a cyclic lipopeptide acylase found in
<0.1% of soil microbes, notably three undescribed Streptomyces and two fungi. Like all echocandins, FR 179642 inhibits the synthesis of 1,3-β-D-glucan in the fungal cell wall. FR 179642 is an important pharmaceutical intermediate for production of the commercial antifungal, micafungin.Please contact us at for specific academic pricing.
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- Properties
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Overview
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