EZ Cap™ Renilla Luc mRNA

Renilla Luc mRNA with Cap 1 structure, providing higher transcription efficiency and enhanced stability.

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Background

EZ Cap™ Renilla Luc mRNA will express Renilla luciferase protein once entering cells, which is initially extracted from enilla reniformis (sea pansy). This enzyme catalyzes Coelenterazine oxidation and lead to yield chemiluminescence at about 480 nm wavelength. Renilla Luc is a frequently used bioluminescent reporter for gene regulation and function study. It is applicable in assays for mRNA delivery, translation efficiency, cell viability and in vivo imaging etc.
EZ Cap™ Renilla Luc mRNA is provided at a concentration of 1mg/ml. It is co-transcriptional capped which generates a cap 1 structure with high efficiency. Cap 1 structure is more ideal for mammalian systems and possesses higher transcription efficiency than Cap 0 structure (ARCA and mCap). The addition of poly (A) tail increases the stability and lifetime of the mRNA in vitro and in vivo. Poly (A) tail also plays an important role in enhancing the efficiency of translation initiation.