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Overview
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Dasatinib is multitarget kinase inhibitor used in the treatment of leukemia. Dasatinib's main targets are tyrosine kinase BCR/ABL, which works to provide the cancer cell with ATP at an uncontrolled rate causing rapid division, and the SRC family of kinases, which contribute to the malignant migration of cancers.
Dasatinib is slightly soluble in ethanol and methanol, but insoluble in water.
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Background
Dasatinib is able to bind to the kinase domain of both the active and inactive forms of BCR/ABL for more effective inhibiting power.
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Overview