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Overview
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Butyrolactone I is one of a family of three butyrolactones isolated from Aspergillus fumigatus, first reported in 1983. Butyrolactone I is a selective inhibitor of cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5, and is an important bioprobe for understanding the cellular roles of CDKs.
Butyrolactone I is soluble in ethanol, methanol, DMF and DMSO.Please contact us at for specific academic pricing.
Background
Butyrolactone I inhibits the cell cycle at the G1/S and G2/M transitions.
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- Properties
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Overview