Cefditoren sodium

- Overview
  - Cefditoren sodium is a third generation cephalosporin antibiotic.
    
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    Background
    
    Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.
- Properties
  - CAS Number
    
    104146-53-4
    
    Molecular Formula
    
    C19H17N6NaO5S3
    
    Molecular Weight
    
    528.56
    
    Appearance
    
    White or white-like crystalline powder
    
    Other Properties
    
    Assay (On Dried Basis): ≥99.0%
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Cefditoren is a broad spectrum antibiotic commonly used against bacteria responsible for community acquired pneumonia and pharyngitis.
    
    Microbiology Applications: Cefditoren sodium can be used to study antibiotic effects against group A Streptococcus and other microbes responsible for phayrngitis.