Cefditoren Pivoxil

- Overview
  - Cefditoren pivoxil is a third-generation cephalosporin antibiotic.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.
- Properties
  - CAS Number
    
    117467-28-4
    
    Molecular Formula
    
    C25H28N6O7S3
    
    Molecular Weight
    
    620.72 g/mol
    
    Appearance
    
    Light yellow or off-white crystalline powder
    
    Other Properties
    
    Assay 944-1005 µg/mg (on dried basis)
    Residue On Ignition: ≤0.2%
    Heavy Metals: ≤10 ppm
    Optical Rotation: -45° - -52°
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Cefditoren is a broad spectrum antibiotic commonly used against bacteria responsible for community acquired pneumonia and pharyngitis
    
    Microbiology Applications: Cefditoren pivoxil can be used to study antibiotic effects against group A Streptococcus and other microbes responsible for phayrngitis.