Avibactam Sodium

- Overview
  - Avibactam Sodium is a β-lactamase inhibitor without a β-lactam core that can inhibit class A and C enzymes, along with some class D enzymes. It is effective against Enterobacteriaceae. Avibactam Sodium can be used for strain manipulation and resistance studies. Avibactam Sodium is soluble in water.
    
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    Background
    
    Avibactam is a nucleophilic serine enzyme inhibitor that contains a diazabicyclooctane (DBO) core, unlike the other β -lactamases, or PBPs (penicillin-binding protein) inhibitors, that contain a β -lactam ring.
- Properties
  - CAS Number
    
    1192491-61-4
    
    Molecular Formula
    
    C7H11N3NaO6S
    
    Molecular Weight
    
    287.23
    
    Solubility
    
    Soluble in water
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Eukaryotic Cell Culture Applications: Avibactam can restore the antimicrobial properties of partner cephalosporins in vitro against Enterobacteriaceae (Lagacé-Wiens et al, 2011).