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Overview
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Antibody to thyroglobulin has been shown to be useful in positive identification of thyroid carcinomas of the papillary and follicular types. Demonstration of thyroglobulin in a metastatic lesion establishes the thyroid origin of the tumor. Adenocarcinomas of non‐thyroidal origin are not reactive. Clone 2H11+6E1 cocktail is especially designed for sensitive detection of thyroglobulin. It stains thyroglobulin in follicular epithelial cells as well as colloid tissue.
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