Anti-NKX2-1 antibody

Catalog Number:

IGA1029451STJ

Mfr. No.:

STJ180262

Price:

$331

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Overview
- TTF‐1(Thyroid transcription factor‐1) is a member of the NKX2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. TTF‐1 is detected in primary lung adenocarcinomas and small cell carcinomas and is absent in colon and breast carcinomas. Staining with TTF‐1 antibody is useful for distinguishing between tumors of lung and non‐ lung origin.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1 kappa
  
  Reactivity
  
  human
  
  Clone
  
  8G7G3/1
  
  Immunogen
  
  Rat TTF‐1 recombinant protein
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
  
  Storage
  
  Store at 2-8°C for up to 1 year
  
  Regulatory Status
  
  RUO
  
  * For research use only