Name: Anti-TIA1 antibody
Price: 331.00 USD

Overview
- The T cell intracellular antigen 1 (TIA‐1) is a 17‐kDa cytoplasmic granule associated protein also designated as GMP‐17, for granule membrane protein of 17 kDa. The GMP‐ 17/TIA‐1 molecule is expressed in cells possessing cytolytic potential and could be involved in the signaling cascade of Fas (CD95)‐mediated apoptosis. Within hematopoietic cell lines, the 2G9 monoclonal antibody (mAb) reacts with about 90% of CD16+, 50 – 60% of CD8+, and less than 10% of CD4+ normal peripheral blood lymphocytes. It reacts with almost all monocytes and granulocytes. This antibody also reacts with CD4+ activated T‐cell clones, activated NK cell clones, and Con activated thymocytes, but not with B lymphocytes or B‐cell lines.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1 kappa
  
  Reactivity
  
  human
  
  Clone
  
  2G9A10F5
  
  Immunogen
  
  Human bone marrow malignant cells from a non‐B, non‐T acute leukemia
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
  
  Storage
  
  Store at 2-8°C for up to 1 year
  
  Regulatory Status
  
  RUO
  
  * For research use only