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Overview
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PAX-8 is a transcription factor expressed during embryonic development of Mllerian organs, kidney, and thyroid, with continued expression in some epithelial cell types of these mature tissues.1 It canbe useful for marking several types of carcinoma including ovarian serous carcinoma, clear cell renalcell carcinoma, and papillary thyroid carcinoma.1-5 Additionally, PAX-8 is not found in the epithelialcells of the breast, lung, mesothelium, stomach, colon, pancreas and other sites.
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Overview