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Overview
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Adenovirus infection is associated with a broad spectrum of clinical disease in both children and adults.It has gained more attention as an important complication in patients who have undergone bonemarrow or solid organ transplantation. The incidence of adenovirus infection in bone marrowtransplant patients has been reported at 5-20%. Adenovirus infection on morphology should bedifferentially diagnosed from other virus infections, especially CMV infection. Anti-adenovirus can assistin this differential diagnosis by showing a round or crescent-shaped nuclear inclusion, generally withinthe surface epithelium and is exclusively intra-nuclear in location.
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Overview