Name: Anti-Human MUM1 antibody
Price: 1631.00 USD

Overview
- Labels a 50kDa, multiple myeloma oncogen-1 (MUM1) protein. MUM1 is encoded by theMUM1/IRF-4 gene, which is mapped to 6q23-25 and identified as a myeloma-associated oncogene. It isa member of the interferon regulatory factor family of transcription factors and plays an important rolein the regulation of gene expression in response to signaling by interferon and other cytokines. MUM1positive cells express the protein in the nucleus in a diffuse and microgranular pattern. However, somepositivity is also observed in the cytoplasm of MUM1-expressing cells. In normal/reactive lymphoidtissues, such as lymph node, this antibody stains plasma cells, some B-cells in the light zone of terminalcenters, and a subset of T-cells (T-cells in germinal centers and interfollicular areas). Anti-MUM1antibody can stain other B-cell lymphomas such as lymphoplasmacytic lymphoma, chronic lymphocyticleukemia, follicular lymphoma, marginal zone lymphoma, lymphoblastic lymphoma/leukemia, primaryeffusion lymphoma, DLBCL, Burkitt-like lymphoma, and classical Hodgkin lymphoma.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Clone
  
  MRQ-43
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Interferon Regulatory Factor 4; Irf-4; Lymphocyte-Specific Interferon Regulatory Factor; Lsirf; Multiple Myeloma Oncogene 1; Nf-Em5 (Gene ID:3662; UniProt:Q15306)
  
  * For research use only