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Overview
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Reacts with all human classical MHC Class I molecules in native cell-surface forms (e.g. itrecognizes native HLA-A2 in flow cytometry and immunoprecipitation but not in Western blotting).MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human nucleated cell types.The antibody MEM-147 is positive in Western blotting (non-reducing conditions) only with most HLA-Band HLA-C molecules, but not HLA-A. Reactivity is very similar to the classical antibody W6/32.Immunogen: PHA-activated peripheral blood lymphocytes
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Overview