Name: Anti-FH antibody
Price: 224.00 USD

Overview
- FH is a protein encoded by the FH gene which is approximately 54, 6 kDa. FH is localised to the cytoplasm and mitochondrion. It is involved in pyruvate metabolism, citric acid cycle and carbon metabolism. It is an enzymatic component of the tricarboxylic acid cycle and catalyses the formation of L-malate from fumarate. It can exist in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. FH is expressed in the cells of the nervous system, liver, skin, kidney and muscle. Mutations in the FH gene may result in fumarase deficiency. STJ96975 was developed from clone 7F1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous FH proteins.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human; mouse; rat
  
  Clone
  
  7F1
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Fumarate Hydratase-Mitochondrial; Fumarase; Hsfh (Gene ID:2271; UniProt:P07954)
  
  * For research use only