Name: Anti-ABCB5 antibody
Price: 224.00 USD

Overview
- ABCB5 is a protein encoded by the ABCB5 gene which is approximately 138, 6 kDa. ABCB5 is localised to the cell membrane. It is involved in CDK-mediated phosphorylation, the removal of Cdc6 and the transport of glucose, bile salts, metal ions and amine compounds. This protein falls under the ATP-binding cassette transporter superfamily of integral membrane proteins. It participates in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules. ABCB5 is expressed in the skin. Mutations in the ABCB5 gene may result in malignant conjunctival melanoma. STJ96976 was developed from clone 11A2 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous ABCB5 proteins.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human
  
  Clone
  
  11A2
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Atp-Binding Cassette Sub-Family B Member 5; Abcb5 P-Gp; P-Glycoprotein Abcb5 (Gene ID:340273; UniProt:Q2M3G0)
  
  * For research use only