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Overview
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Is a useful marker for staining many carcinomas. It stains normal and neoplastic cells fromvarious tissues, including mammary epithelium, sweat glands and colorectal carcinoma. Hepatocellularcarcinoma, adrenal carcinoma and embryonal carcinomas are consistently EMA negative, so keratinpositivity with negative EMA favors one of these tumors. EMA is frequently positive in meningioma, which can be useful when distinguishing it from other intracranial neoplasms such as schwannomas.
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Overview